Diagnosis of bacterial vaginosis: Comparison of Nugent´s and novel microscopic method

Background/Aim. Bacterial vaginosis (BV) is a common cause of vaginal discomfort in women. The aim this study was to compare Nugent?s scoring system and novel microscopy method, introduced our laboratory used BV diagnosis. Methods. This included 705 pregnant asymptomatic women between 24 28 weeks pregnancy. degree agreement methods determined by the kappa (?) index. sensitivity, specificity, positive negative predictive value method compared score as standard. Results. Based on both methods, diagnosed 21% 25% women, respectively. Despite disparities among diagnostic criteria, which mainly concerned classification intermediary samples, categories, ? index, satisfactory: vs. (? = 0.68; good agreement), without results 0.83; very agreement). We also demonstrated that golden standard, had high sensitivity specificity (ranging from 75%?99.3%) values 88.8%?99.5%). Our based relative number bacterial morphotypes, either rod forms 1.5 ?m, lactobacilli) or non-rod (< associated bacteria) under 200? magnification, extends surface examined preparation, but prolongation observer?s working time. Conclusion. diagnosing corresponded well with allows it be an alternative BV. Further-more, morphotypes appeared flexible can reorganized way categorize findings into only two groups: normal BV, makes comparable dichotomous Amsel?s clinical criterion.